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Substrate affinity of photosensitizers derived from chlorophyll-a: The ABCG2 transporter affects the phototoxic response of side population stem cell-like cancer cells to photodynamic therapy

Photosensitizers (PS) synthesized with the aim of optimizing photodynamic therapy (PDT) of tumors do not always fulfill their potential when tested in vitro and in vivo in different tumor models. The ATP-dependent transporter ABCG2 a multi-drug resistant pump expressed at variable levels in cancerou...

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Hlavní autoři: Morgan, Janet, Jackson, Jennifer D., Zheng, Xiang, Pandey, Suresh K., Pandey, Ravindra K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017217/
https://ncbi.nlm.nih.gov/pubmed/20684544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100154j
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