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Effect of chirality on cellular uptake, imaging and photodynamic therapy of photosensitizers derived from chlorophyll-a

We have previously shown that the (124)I-analog of methyl 3-(1’-m-iodobenzyloxy) ethyl-3-devinyl-pyropheophorbide-a derived as racemic mixture from chlorophyll-a can be used for PET (positron emission tomography) -imaging in animal tumor models. On the other hand, as a non-radioactive analog, it sho...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Srivatsan, Avinash, Pera, Paula, Joshi, Penny, Wang, Yanfang, Missert, Joseph R., Tracy, Erin C., Tabaczynski, Walter A., Yao, Rutao, Sajjad, Munawwar, Baumann, Heinz, Pandey, Ravindra K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461543/
https://ncbi.nlm.nih.gov/pubmed/25936263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.04.006
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