Visualizing key hinges and a potential major source of compliance in the lever arm of myosin

We have determined the 2.3-Å-resolution crystal structure of a myosin light chain domain, corresponding to one type found in sea scallop catch (“smooth”) muscle. This structure reveals hinges that may function in the “on” and “off” states of myosin. The molecule adopts two different conformations ab...

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Detalles Bibliográficos
Autores principales: Brown, Jerry H., Senthil Kumar, V. S., O’Neall-Hennessey, Elizabeth, Reshetnikova, Ludmila, Robinson, Howard, Nguyen-McCarty, Michelle, Szent-Györgyi, Andrew G., Cohen, Carolyn
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017161/
https://ncbi.nlm.nih.gov/pubmed/21149681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016288107
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