Visualizing key hinges and a potential major source of compliance in the lever arm of myosin

We have determined the 2.3-Å-resolution crystal structure of a myosin light chain domain, corresponding to one type found in sea scallop catch (“smooth”) muscle. This structure reveals hinges that may function in the “on” and “off” states of myosin. The molecule adopts two different conformations ab...

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Detalhes bibliográficos
Main Authors: Brown, Jerry H., Senthil Kumar, V. S., O’Neall-Hennessey, Elizabeth, Reshetnikova, Ludmila, Robinson, Howard, Nguyen-McCarty, Michelle, Szent-Györgyi, Andrew G., Cohen, Carolyn
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017161/
https://ncbi.nlm.nih.gov/pubmed/21149681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016288107
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