Visualizing key hinges and a potential major source of compliance in the lever arm of myosin

We have determined the 2.3-Å-resolution crystal structure of a myosin light chain domain, corresponding to one type found in sea scallop catch (“smooth”) muscle. This structure reveals hinges that may function in the “on” and “off” states of myosin. The molecule adopts two different conformations ab...

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Bibliografski detalji
Glavni autori: Brown, Jerry H., Senthil Kumar, V. S., O’Neall-Hennessey, Elizabeth, Reshetnikova, Ludmila, Robinson, Howard, Nguyen-McCarty, Michelle, Szent-Györgyi, Andrew G., Cohen, Carolyn
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017161/
https://ncbi.nlm.nih.gov/pubmed/21149681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016288107
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