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The On-off Switch in Regulated Myosins: Different Triggers but Related Mechanisms

In regulated myosins, motor and enzymatic activity are toggled between on- and off-states by a switch located on its lever arm, or regulatory domain (RD). This region consists of a long alpha-helical "heavy chain" stabilized by a "regulatory" and an "essential" light ch...

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Main Authors: Himmel, Daniel M., Mui, Suet, O'Neall-Hennessey, Elizabeth, Szent-Györgyi, Andrew G., Cohen, Carolyn
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997636/
https://ncbi.nlm.nih.gov/pubmed/19769984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.09.035
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