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Self-specific CD8+ T cells maintain a semi-naïve state following lymphopenia-induced proliferation
Upon transfer into T-cell deficient hosts, naïve CD8+ T cells typically undergo “lymphopenia-induced proliferation” (LIP, also called “homeostatic proliferation”), and develop the phenotypic and functional characteristics of memory CD8+ T cells. However, the capacity of T cells with self-peptide/MHC...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3016941/ https://ncbi.nlm.nih.gov/pubmed/20393139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000109 |
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