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Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences

BACKGROUND: The human IGF2-P4 and H19 promoters are highly active in a variety of human cancers (including bladder cancer), while existing at a nearly undetectable level in the surrounding normal tissue. Single promoter vectors expressing diphtheria toxin A-fragment (DTA) under the control regulatio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Amit, Doron, Hochberg, Abraham
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016259/
https://ncbi.nlm.nih.gov/pubmed/21162716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-134
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