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Physicochemical properties of pore residues predict activation gating of Ca(V)1.2: A correlation mutation analysis
Single point mutations in pore-forming S6 segments of calcium channels may transform a high-voltage-activated into a low-voltage-activated channel, and resulting disturbances in calcium entry may cause channelopathies (Hemara-Wahanui et al., Proc Natl Acad Sci U S A 102(21):7553–7558, 16). Here we a...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3016219/ https://ncbi.nlm.nih.gov/pubmed/20924598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-010-0885-2 |
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