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Preferential Binding of β(S) Globin Chains Associated with Stroma in Sickle Cell Disorders

Sickle cell anemia (SS) is associated with abnormalities of the red cell membrane and decreased red cell deformability. The present study assesses globin chain binding to stroma in SS, sickle cell trait (AS), and nonsickling (AA) cells. The results indicate that there is preferential binding of newl...

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Publicado en:J Clin Invest
Autores principales: Bank, Arthur, Mears, Gregory, Weiss, Robert, O'Donnell, Joyce V., Natta, Clayton
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1974
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301620/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4430714/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107820
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