Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.
Restriction endonuclease mapping of the human globin genes revealed a genetic variation in a Hpa I recognition site about 5000 nucleotides from the 3' end of the beta-globin structural gene. Instead of a normal 7.6-kilobase (kb) fragment which contains the beta-globin structural gene, 7.0-kb and 13....
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1978
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393021/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/281713/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.11.5631 |
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