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Preferential Binding of β(S) Globin Chains Associated with Stroma in Sickle Cell Disorders

Sickle cell anemia (SS) is associated with abnormalities of the red cell membrane and decreased red cell deformability. The present study assesses globin chain binding to stroma in SS, sickle cell trait (AS), and nonsickling (AA) cells. The results indicate that there is preferential binding of newl...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Bank, Arthur, Mears, Gregory, Weiss, Robert, O'Donnell, Joyce V., Natta, Clayton
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301620/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4430714/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107820
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