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Cleavable Biotin Probes for Labeling of Biomolecules via the Azide – Alkyne Cycloaddition

The azide-alkyne cycloaddition provides a powerful tool for bio-orthogonal labeling of proteins, nucleic acids, glycans, and lipids. In some labeling experiments, e.g., in proteomic studies involving affinity purification and mass spectrometry, it is convenient to use cleavable probes that allow rel...

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Bibliographic Details
Main Authors: Szychowski, Janek, Mahdavi, Alborz, Hodas, Jennifer J. L., Bagert, John D., Ngo, John T., Landgraf, Peter, Dieterich, Daniela C., Schuman, Erin M., Tirrell, David A.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016050/
https://ncbi.nlm.nih.gov/pubmed/21141861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1083909
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