Innate immune activation by the viral PAMP poly I:C potentiates pulmonary graft-versus-host disease after allogeneic hematopoietic cell transplant

Respiratory viral infections cause significant morbidity and increase the risk for chronic pulmonary graft-versus-host disease (GVHD) after hematopoietic cell transplantation (HCT). Our overall hypothesis is that local innate immune activation potentiates adaptive alloimmunity. In this study, we hyp...

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Detalhes bibliográficos
Main Authors: Kinnier, Christine V, Martinu, Tereza, Gowdy, Kymberly, Nugent, Julia L, Kelly, Francine L, Palmer, Scott M
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3015000/
https://ncbi.nlm.nih.gov/pubmed/21070856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trim.2010.11.004
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