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Interferon alpha Accelerates Murine SLE in a T Cell Dependent Manner

OBJECTIVE: To investigate the mechanism for lupus acceleration by interferon alpha (IFNα) in NZB/W mice. METHODS: NZB/W mice were treated with an adenovirus expressing IFNα. T cells were depleted in some mice with an anti-CD4 antibody. The production of anti-dsDNA antibodies was measured by ELISA an...

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Detalhes bibliográficos
Main Authors: Liu, Zheng, Bethunaickan, Ramalingam, Huang, Weiqing, Lodhi, Umairullah, Solano, Ingrid, Madaio, Michael P., Davidson, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014995/
https://ncbi.nlm.nih.gov/pubmed/20954185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30087
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