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The Pitx2c N-terminal domain is a critical interaction domain required for asymmetric morphogenesis

The paired-like homeodomain transcription factor Pitx2c has an essential role in patterning the left-right axis. However, neither its transcriptional targets nor the molecular mechanisms through which it exerts its patterning function are known. Here we provide evidence that the N-terminal domain of...

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Autores principales: Simard, Annie, Di Giorgio, Luciano, Amen, Melanie, Westwood, Ashley, Amendt, Brad A., Ryan, Aimee K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014603/
https://ncbi.nlm.nih.gov/pubmed/19681163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22062
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