Tbx1 Regulates Progenitor Cell Proliferation in the Dental Epithelium by Modulating PITX2 Activation of p21

Tbx1(−/−) mice present with phenotypic effects observed in DiGeorge syndrome patients however, the molecular mechanisms of Tbx1 regulating craniofacial and tooth development are unclear. Analyses of the Tbx1 null mice reveal incisor microdontia, small cervical loops and BrdU labeling reveals a defec...

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Hlavní autoři: Cao, Huojun, Florez, Sergio, Amen, Melanie, Huynh, Tuong, Skobe, Ziedonis, Baldini, Antonio, Amendt, Brad A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334818/
https://ncbi.nlm.nih.gov/pubmed/20816801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.08.031
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