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Tbx1 regulates proliferation and differentiation of multipotent heart progenitors

RATIONALE: TBX1 encodes a T-box transcription factor implicated in DiGeorge syndrome, which affects the development of many organs, including the heart. Loss of Tbx1 results into hypoplasia of heart regions derived from the second heart field (SHF), a population of cardiac progenitors cells (CPCs)....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Li, Fulcoli, Filomena Gabriella, Tang, Susan, Baldini, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796444/
https://ncbi.nlm.nih.gov/pubmed/19745164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.200295
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