Verapamil Protects Dopaminergic Neuron Damage through a Novel Anti-inflammatory Mechanism by Inhibition of Microglial Activation

Verapamil has been shown to be neuroprotective in several acute neurotoxicity models due to blockade of calcium entry into neurons. However, the potential use of verapamil to treat chronic neurodegenerative diseases has not been reported. Using rat primary mesencephalic neuron/glia cultures, we repo...

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Detalhes bibliográficos
Main Authors: Liu, Yuxin, Lo, Yi-Ching, Qian, Li, Crews, Fulton Tim, Wilson, Belinda, Chen, Hui-Ling, Wu, Hung-Ming, Chen, Shih-Heng, Wei, Ke, Lu, Ru-Band, Ali, Syed, Hong, Jau-Shyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014428/
https://ncbi.nlm.nih.gov/pubmed/20950631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.10.002
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