Verapamil Protects Dopaminergic Neuron Damage through a Novel Anti-inflammatory Mechanism by Inhibition of Microglial Activation

Verapamil has been shown to be neuroprotective in several acute neurotoxicity models due to blockade of calcium entry into neurons. However, the potential use of verapamil to treat chronic neurodegenerative diseases has not been reported. Using rat primary mesencephalic neuron/glia cultures, we repo...

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Main Authors: Liu, Yuxin, Lo, Yi-Ching, Qian, Li, Crews, Fulton Tim, Wilson, Belinda, Chen, Hui-Ling, Wu, Hung-Ming, Chen, Shih-Heng, Wei, Ke, Lu, Ru-Band, Ali, Syed, Hong, Jau-Shyong
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014428/
https://ncbi.nlm.nih.gov/pubmed/20950631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.10.002
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