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Selective Macrophage Ascorbate Deficiency Suppresses Early Atherosclerosis

To test whether severe ascorbic acid deficiency in macrophages affects progression of early atherosclerosis, we used fetal liver cell transplantation to generate atherosclerosis-prone apolipoprotein E-deficient (apoE(−/−)) mice that selectively lacked the ascorbate transporter (SVCT2) in hematopoiet...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Babaev, Vladimir R., Whitesell, Richard R., Li, Liying, Linton, MacRae F., Fazio, Sergio, May, James M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014415/
https://ncbi.nlm.nih.gov/pubmed/20974251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.10.702
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