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Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis
Prostagladin (PG) E(2), a major product of activated macrophages, has been implicated in atherosclerosis and plaque rupture. The PGE(2) receptors, EP2 and EP4, are expressed in atherosclerotic lesions and are known to inhibit apoptosis in cancer cells. To examine the roles of macrophage EP4 and EP2...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614698/ https://ncbi.nlm.nih.gov/pubmed/19041765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.09.005 |
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