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Gel structure impacts pericellular and extracellular matrix deposition which subsequently alters metabolic activities in chondrocyte-laden PEG hydrogels

While designing poly(ethylene glycol) hydrogels with high moduli suitable for in situ placement is attractive for cartilage regeneration, the impact of a tighter crosslinked structure on the organization and deposition of matrix is not fully understood. The objectives for this study were to characte...

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Main Authors: Nicodemus, G.D., Skaalure, S.C., Bryant, S.J.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014397/
https://ncbi.nlm.nih.gov/pubmed/20804868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2010.08.021
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