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Static and dynamic compressive strains influence nitric oxide production and chondrocyte bioactivity when encapsulated in PEG hydrogels of different crosslinking densities

OBJECTIVE: Mechanical loading is an important regulator of chondrocytes; however, many of the mechanisms involved in chondrocyte mechanotransduction still remain unclear. Here, poly(ethylene glycol) (PEG) hydrogels are proposed as a model system to elucidate chondrocyte response due to cell deformat...

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Autors principals: Villanueva, I, Hauschulz, DS, Mejic, D, Bryant, SJ
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307988/
https://ncbi.nlm.nih.gov/pubmed/18203631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2007.12.003
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