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Roles of Vaccinia Virus Genes E3L and K3L and Host Genes PKR and RNase L during Intratracheal Infection of C57BL/6 Mice

The importance of the 2′-5′ oligoadenylate synthetase (OAS)/RNase L and double-stranded RNA (dsRNA)-dependent protein kinase (PKR) pathways in host interferon induction resulting from virus infection in response to dsRNA has been well documented. In poxvirus infections, the interactions between the...

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Auteurs principaux: Rice, Amanda D., Turner, Peter C., Embury, Jennifer E., Moldawer, Lyle L., Baker, Henry V., Moyer, Richard W.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014211/
https://ncbi.nlm.nih.gov/pubmed/20943971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00254-10
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