Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase– and cathepsin-dependent emphysema

Cigarette smoke exposure is the major cause of chronic obstructive pulmonary disease (COPD). However, only a minority of smokers develop significant COPD, and patients with asthma or asthma-like airway hyperresponsiveness or eosinophilia experience accelerated loss of lung function after cigarette s...

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Pubblicato in:J Clin Invest
Autori principali: Zheng, Tao, Zhu, Zhou, Wang, Zhongde, Homer, Robert J., Ma, Bing, Riese, Richard J., Chapman, Harold A., Shapiro, Steven D., Elias, Jack A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2000
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Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301418/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11067861/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI10458
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