Matrix Metalloproteinase 12-Deficiency Augments Extracellular Matrix Degrading Metalloproteinases and Attenuates IL-13–Dependent Fibrosis

Infection with the parasitic helminth Schistosoma mansoni causes significant liver fibrosis and extracellular matrix (ECM) remodeling. Matrix metalloproteinases (MMP) are important regulators of the ECM by regulating cellular inflammation, extracellular matrix deposition, and tissue reorganization....

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Bibliografiset tiedot
Päätekijät: Madala, Satish K., Pesce, John T., Ramalingam, Thirumalai R., Wilson, Mark S., Minnicozzi, Samantha, Cheever, Allen W., Thompson, Robert W., Mentink-Kane, Margaret M., Wynn, Thomas A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175622/
https://ncbi.nlm.nih.gov/pubmed/20181883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903008
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