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A GNAS1 imprinting defect in pseudohypoparathyroidism type IB

Pseudohypoparathyroidism type IB (PHPIB) is characterized by renal resistance to parathyroid hormone (PTH) and the absence of other endocrine or physical abnormalities. Familial PHPIB has been mapped to 20q13, near GNAS1, which encodes G(s)α, the G protein α-subunit required for receptor-stimulated...

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Autors principals: Liu, Jie, Litman, Deborah, Rosenberg, Marjorie J., Yu, Shuhua, Biesecker, Leslie G., Weinstein, Lee S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC301417/
https://ncbi.nlm.nih.gov/pubmed/11067869
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