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A GNAS1 imprinting defect in pseudohypoparathyroidism type IB

Pseudohypoparathyroidism type IB (PHPIB) is characterized by renal resistance to parathyroid hormone (PTH) and the absence of other endocrine or physical abnormalities. Familial PHPIB has been mapped to 20q13, near GNAS1, which encodes G(s)α, the G protein α-subunit required for receptor-stimulated...

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Detalhes bibliográficos
Main Authors: Liu, Jie, Litman, Deborah, Rosenberg, Marjorie J., Yu, Shuhua, Biesecker, Leslie G., Weinstein, Lee S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC301417/
https://ncbi.nlm.nih.gov/pubmed/11067869
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