Evaluation of Psn, HmuR and a modified LcrV protein delivered to mice by live attenuated Salmonella as a vaccine against bubonic and pneumonic Yersinia pestis challenge

We evaluated the ability of Yersinia pestis antigens HmuR, Psn and modified forms of LcrV delivered by live attenuated Salmonella strains to stimulate a protective immune response against subcutaneous or intranasal challenge with Y. pestis CO92. LcrV196 is a previously described truncated protein th...

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Autori principali: Branger, Christine G., Sun, Wei, Torres-Escobar, Ascención, Perry, Robert, Roland, Kenneth L., Fetherston, Jacqueline, Curtiss, Roy
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014047/
https://ncbi.nlm.nih.gov/pubmed/20979987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.10.033
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