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Oral Vaccination with LcrV from Yersinia pestis KIM delivered by live attenuated Salmonella enterica serovar Typhimurium elicits a protective immune response against challenge with Yersinia pseudotuberculosis and Yersinia enterocolitica

The use of live recombinant attenuated Salmonella vaccines (RASV) synthesizing Yersinia proteins is a promising approach for controlling infection by Yersinia species. In this study, we constructed attenuated Salmonella strains which synthesize a truncated form of LcrV, LcrV196 and evaluated the imm...

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Detalhes bibliográficos
Main Authors: Branger, Christine G., Torres-Escobar, Ascención, Sun, Wei, Perry, Robert, Fetherston, Jacqueline, Roland, Kenneth L., Curtiss, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751733/
https://ncbi.nlm.nih.gov/pubmed/19596407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.06.078
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