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Heme Oxygenase-1 Inhibits Renal Tubular Macroautophagy in Acute Kidney Injury
Autophagy is a tightly regulated, programmed mechanism to eliminate damaged organelles and proteins from a cell to maintain homeostasis. Cisplatin, a chemotherapeutic agent, accumulates in the proximal tubules of the kidney and causes dose-dependent nephrotoxicity, which may involve autophagy. In th...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Nephrology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3013546/ https://ncbi.nlm.nih.gov/pubmed/20705711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010030238 |
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