Deletion of the pH Sensor GPR4 Decreases Renal Acid Excretion

Proton receptors are G protein-coupled receptors that accept protons as ligands and function as pH sensors. One of the proton receptors, GPR4, is relatively abundant in the kidney, but its potential role in acid-base homeostasis is unknown. In this study, we examined the distribution of GPR4 in the...

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Главные авторы: Sun, Xuming, Yang, Li V., Tiegs, Brian C., Arend, Lois J., McGraw, Dennis W., Penn, Raymond B., Petrovic, Snezana
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2010
Предметы:
Basic Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013533/
https://ncbi.nlm.nih.gov/pubmed/20798260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009050477
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