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The extended life span of Drosophila melanogaster eye-color (white and vermilion) mutants with impaired formation of kynurenine
Animal and human studies suggest that aging is associated with increased formation of kynurenine (KYN) from tryptophan (TRY). The rate-limiting factors of TRY–KYN metabolism are transmembrane transport of TRY, and activity of enzyme, TRY 2,3-dioxygenase (TDO2). Eye-color mutants, white (w1118) (impa...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3013506/ https://ncbi.nlm.nih.gov/pubmed/19941150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-009-0341-7 |
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