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Extension of life span of Drosophila melanogaster by the inhibitors of tryptophan-kynurenine metabolism
Upregulation of kynurenine (KYN) formation from tryptophan (TRY) was associated with aging in animal and human studies. TRY-KYN metabolism is affected by the activities of TRY 2,3-dioxygenase 2 (TDO) and AT P-binding cassette (ABC) transporter regulating TRY access to intracellular TDO. We studied t...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3266072/ https://ncbi.nlm.nih.gov/pubmed/22041575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/fly.5.4.18414 |
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