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Minocycline Effect on Life and Health Span of Drosophila Melanogaster
Up-regulation of kynurenine (KYN) pathway of tryptophan (TRP) was suggested as one of the mechanisms of aging and aging-associated disorders. Genetic and pharmacological impairment of TRP – KYN metabolism resulted in prolongation of life span in Drosophila models. Minocycline, an antibiotic with ant...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
JKL International LLC
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501391/ https://ncbi.nlm.nih.gov/pubmed/23185716 |
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