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Identification of ciliary neurotrophic factor receptor alpha as a mediator of neurotoxicity induced by α-synuclein

Accumulating evidence suggests that extracellular α-synuclein (eSNCA) plays an important role in the pathogenesis of Parkinson's disease (PD) or related synucleinopathies by inducing neurotoxicity directly or indirectly via microglial or astroglial activation. However, the mechanisms by which t...

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Hlavní autoři: Liu, Jun, Shi, Min, Hong, Zhen, Zhang, JianPeng, Bradner, Joshua, Quinn, Thomas, Beyer, Richard P., Mcgeer, Patrick L., Chen, ShengDi, Zhang, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013276/
https://ncbi.nlm.nih.gov/pubmed/20340160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200900745
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