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Gi2-mediated activation of the MAP kinase cascade.

The Gi class of heterotrimeric G proteins has been implicated in transmitting mitogenic signals from a variety of seven-transmembrane domain receptors. In addition, the alpha subunit of Gi2 (alpha i2) is oncogenic when mutated to a constitutively active form (gip2). The mechanism by which Gi2 stimul...

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Bibliografiske detaljer
Main Authors: Pace, A M, Faure, M, Bourne, H R
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC301325/
https://ncbi.nlm.nih.gov/pubmed/8590798
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