A mutant alpha subunit of Gi2 induces neoplastic transformation of Rat-1 cells.

In a recently discovered class of oncogenes, GTPase-inhibiting mutations constitutively activate alpha subunits of signal-transducing guanine nucleotide-binding proteins (G proteins). Somatic mutations in a subclass of endocrine tumors are found in the arginine-179 codon of the alpha subunit of Gi2...

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Detaylı Bibliyografya
Asıl Yazarlar: Pace, A M, Wong, Y H, Bourne, H R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1991
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC52227/
https://ncbi.nlm.nih.gov/pubmed/1651490
Etiketler: Etiketle
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