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Duplicated Gephyrin Genes Showing Distinct Tissue Distribution and Alternative Splicing Patterns Mediate Molybdenum Cofactor Biosynthesis, Glycine Receptor Clustering, and Escape Behavior in Zebrafish

Gephyrin mediates the postsynaptic clustering of glycine receptors (GlyRs) and GABA(A) receptors at inhibitory synapses and molybdenum-dependent enzyme (molybdoenzyme) activity in non-neuronal tissues. Gephyrin knock-out mice show a phenotype resembling both defective glycinergic transmission and mo...

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Detalhes bibliográficos
Main Authors: Ogino, Kazutoyo, Ramsden, Sarah L., Keib, Natalie, Schwarz, Günter, Harvey, Robert J., Hirata, Hiromi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013040/
https://ncbi.nlm.nih.gov/pubmed/20843816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.125500
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