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Duplicated Gephyrin Genes Showing Distinct Tissue Distribution and Alternative Splicing Patterns Mediate Molybdenum Cofactor Biosynthesis, Glycine Receptor Clustering, and Escape Behavior in Zebrafish

Gephyrin mediates the postsynaptic clustering of glycine receptors (GlyRs) and GABA(A) receptors at inhibitory synapses and molybdenum-dependent enzyme (molybdoenzyme) activity in non-neuronal tissues. Gephyrin knock-out mice show a phenotype resembling both defective glycinergic transmission and mo...

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Bibliografski detalji
Glavni autori: Ogino, Kazutoyo, Ramsden, Sarah L., Keib, Natalie, Schwarz, Günter, Harvey, Robert J., Hirata, Hiromi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013040/
https://ncbi.nlm.nih.gov/pubmed/20843816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.125500
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