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Duplicated Gephyrin Genes Showing Distinct Tissue Distribution and Alternative Splicing Patterns Mediate Molybdenum Cofactor Biosynthesis, Glycine Receptor Clustering, and Escape Behavior in Zebrafish

Gephyrin mediates the postsynaptic clustering of glycine receptors (GlyRs) and GABA(A) receptors at inhibitory synapses and molybdenum-dependent enzyme (molybdoenzyme) activity in non-neuronal tissues. Gephyrin knock-out mice show a phenotype resembling both defective glycinergic transmission and mo...

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書誌詳細
主要な著者: Ogino, Kazutoyo, Ramsden, Sarah L., Keib, Natalie, Schwarz, Günter, Harvey, Robert J., Hirata, Hiromi
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013040/
https://ncbi.nlm.nih.gov/pubmed/20843816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.125500
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