Negative Regulation of EGFR-Vav2 Signaling Axis by Cbl Ubiquitin Ligase Controls EGF Receptor-mediated Epithelial Cell Adherens Junction Dynamics and Cell Migration

The E3 ubiquitin ligase Casitas B lymphoma protein (Cbl) controls the ubiquitin-dependent degradation of EGF receptor (EGFR), but its role in regulating downstream signaling elements with which it associates and its impact on biological outcomes of EGFR signaling are less clear. Here, we demonstrate...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Duan, Lei, Raja, Srikumar M., Chen, Gengsheng, Virmani, Sumeet, Williams, Stetson H., Clubb, Robert J., Mukhopadhyay, Chandrani, Rainey, Mark A., Ying, Guoguang, Dimri, Manjari, Chen, Jing, Reddi, Alagarsamy L., Naramura, Mayumi, Band, Vimla, Band, Hamid
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013022/
https://ncbi.nlm.nih.gov/pubmed/20940296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.188086
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires