Cardiac Troponin T, a Sarcomeric AKAP, Tethers Protein Kinase A at the Myofilaments

Efficient and specific phosphorylation of PKA substrates, elicited in response to β-adrenergic stimulation, require spatially confined pools of PKA anchored in proximity of its substrates. PKA-dependent phosphorylation of cardiac sarcomeric proteins has been the subject of intense investigations. Ye...

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Hlavní autoři: Sumandea, C. Amelia, Garcia-Cazarin, Mary L., Bozio, Catherine H., Sievert, Gail A., Balke, C. William, Sumandea, Marius P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013013/
https://ncbi.nlm.nih.gov/pubmed/21056973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.148684
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