Negative Regulation of TGFβ Signaling by the Kinase LKB1 and the Scaffolding Protein LIP1

Signal transduction by the Smad pathway elicits critical biological responses to many extracellular polypeptide factors, including TGFβ and bone morphogenetic protein. Regulation of Smad signaling imparts several cytoplasmic and nuclear mechanisms, some of which entail protein phosphorylation. Previ...

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Main Authors: Morén, Anita, Raja, Erna, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012991/
https://ncbi.nlm.nih.gov/pubmed/20974850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.190660
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