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pH-dependent Studies Reveal an Efficient Hydroxylation Mechanism of the Oxygenase Component of p-Hydroxyphenylacetate 3-Hydroxylase

p-Hydroxyphenylacetate (HPA) 3-hydroxylase (HPAH) catalyzes the hydroxylation of HPA at the ortho-position to yield 3,4-dihydroxyphenylacetate. The enzyme is a flavin-dependent two-component monooxygenase that consists of a reductase component and an oxygenase component (C(2)). C(2) catalyzes the hy...

詳細記述

保存先:
書誌詳細
主要な著者: Ruangchan, Nantidaporn, Tongsook, Chanakan, Sucharitakul, Jeerus, Chaiyen, Pimchai
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012978/
https://ncbi.nlm.nih.gov/pubmed/21030590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163881
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