OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution

Eukaryotic cells harbor a small multiploid mitochondrial genome, organized in nucleoids spread within the mitochondrial network. Maintenance and distribution of mitochondrial DNA (mtDNA) are essential for energy metabolism, mitochondrial lineage in primordial germ cells, and to prevent mtDNA instabi...

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Main Authors: Elachouri, Ghizlane, Vidoni, Sara, Zanna, Claudia, Pattyn, Alexandre, Boukhaddaoui, Hassan, Gaget, Karen, Yu-Wai-Man, Patrick, Gasparre, Giuseppe, Sarzi, Emmanuelle, Delettre, Cécile, Olichon, Aurélien, Loiseau, Dominique, Reynier, Pascal, Chinnery, Patrick F., Rotig, Agnès, Carelli, Valerio, Hamel, Christian P., Rugolo, Michela, Lenaers, Guy
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2011
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012919/
https://ncbi.nlm.nih.gov/pubmed/20974897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.108696.110
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