Lysophosphatidic Acid Induces MDA-MB-231 Breast Cancer Cells Migration through Activation of PI3K/PAK1/ERK Signaling

BACKGROUND: Enhanced motility of cancer cells is a critical step in promoting tumor metastasis. Lysophosphatidic acid (LPA), representing the major mitogenic activity in serum, stimulates migration in various types of cancer cells. However, the underlying signaling mechanisms for LPA-induced motilit...

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Detaylı Bibliyografya
Asıl Yazarlar: Du, Jun, Sun, Chongqi, Hu, Zhenzhen, Yang, Yu, Zhu, Yichao, Zheng, Datong, Gu, Luo, Lu, Xiang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012724/
https://ncbi.nlm.nih.gov/pubmed/21209852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015940
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