Activation of Rac1-PI3K/Akt is required for epidermal growth factor-induced PAK1 activation and cell migration in MDA-MB-231 breast cancer cells()

Epidermal growth factor (EGF) may increase cell motility, an event implicated in cancer cell invasion and metastasis. However, the underlying mechanisms for EGF-induced cell motility remain elusive. In this study, we found that EGF treatment could activate Ras-related C3 botulinum toxin substrate 1...

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Detalhes bibliográficos
Main Authors: Yang, Yu, Du, Jun, Hu, Zhenzhen, Liu, Jiaojing, Tian, Yinhui, Zhu, Yichao, Wang, Le, Gu, Luo
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597073/
https://ncbi.nlm.nih.gov/pubmed/23554696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1674-8301(11)60032-8
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