Lysophosphatidic Acid Induces MDA-MB-231 Breast Cancer Cells Migration through Activation of PI3K/PAK1/ERK Signaling

BACKGROUND: Enhanced motility of cancer cells is a critical step in promoting tumor metastasis. Lysophosphatidic acid (LPA), representing the major mitogenic activity in serum, stimulates migration in various types of cancer cells. However, the underlying signaling mechanisms for LPA-induced motilit...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Du, Jun, Sun, Chongqi, Hu, Zhenzhen, Yang, Yu, Zhu, Yichao, Zheng, Datong, Gu, Luo, Lu, Xiang
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012724/
https://ncbi.nlm.nih.gov/pubmed/21209852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015940
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