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High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients

BACKGROUND: Peutz-Jeghers syndrome (PJS) is a rare autosomal dominantly inherited disease characterized by gastrointestinal hamartomatous polyposis and mucocutaneous pigmentation. The genetic predisposition for PJS has been shown to be associated with germline mutations in the STK11/LKB1 tumor suppr...

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Autors principals: Papp, Janos, Kovacs, Marietta Eva, Solyom, Szilvia, Kasler, Miklos, Børresen-Dale, Anne-Lise, Olah, Edith
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012662/
https://ncbi.nlm.nih.gov/pubmed/21118512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-169
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